Detection of group A streptococcal antigen directly from throat swabs with a ten-minute latex agglutination test

Abstract

Results obtained with the Culturette brand 10-Minute Group A Strep ID system were compared with culture results to measure the ability of this system to detect group A streptococci directly from more than 800 throat swabs. Our study showed a sensitivity of 92.4% and a specificity of 92.8% for this acid extraction, latex agglutination method when compared with anaerobic culturing for group A streptococci. The results suggest that the 10-Minute Group A Strep ID method may prove to be a useful, very rapid and easy method for diagnosing group A streptococcal pharyngitis directly from throat swabs. Further studies are suggested to determine whether this diagnostic method could stand alone or would have to be used in conjunction with culture.