Odontogenic myxofbroma: A concise review of the literature with emphasis on the surgical approach

Abstract

Purpose: The aim of this work is to report a review of the literature concerning epidemiology, clinical and radio-graphic features as well as treatment of odontogenic myxofbroma (MF). Methods: The PubMed database was searched using the following keywords: “odontogenic myxofbroma”, “odon-togenic fbromyxoma”, “myxofbroma of the jaw” and “fbromyxoma of the jaw”. Results: Fifteen articles reporting the experience with 24 patients were identifed. Male/female ratio was 1:1.4 and the average age was 29.5 years. The most frequent location was the mandible. In 66.7% of the cases the ra-diographic appearance was a multilocular radiolucency. Swelling was observed in 13 patients (92.86%), varying degrees of pain in 5 (35.71%) and paresthesia in only one patient (7.14%). Six out of 24 patients (26.09%) were treated with radical surgery and 17 (73.91%) with a conservative approach. In two out of 21 cases (9.52%) a recurrence was reported. Conclusions: MF is an extremely rare tumor and no agreement exists on the causes of its development. According to the present review, the choice of treatment should depend on variables such as localization, presence of a primary or of a recurrent lesion, age, general medical conditions and aesthetic needs of the patient.