Berry Supplementation and Their Beneficial Effects on Some Central Nervous System Disorders

Abstract

Some of the authors of this publication are also working on these related projects: Effect of cherry on monosodium urate crystal-induced oxidative stress View project Effect of anthocyanins and natural compounds from tortilla in cancer therapy View project Rafael Fernández-Demeneghi Universidad Veracruzana Abstract This chapter is based in the compilation and analysis of different in vitro, preclinical, and clinical studies, which explored the potential beneficial bioactiv-ity of supplementation with berries on some alterations in the central nervous system (CNS). The last section of the chapter describes the possible mechanisms of action of polyphenols, anthocyanins, and other compounds present in berries as well as their relationship with anxiety, depression, and Alzheimer's (AD) and Parkinson's diseases (PD) and their implication in the prevention of cogni-tive decline and senescence motor functions. Electronic databases as Springer, PubMed, Scopus, and Elsevier were used. Papers were selected by topic specially those related with berries, year of publication, and authors. The present chapter evidenced the potential health effect as neuroprotector of different berries and their bioactive compounds mainly flavonoids, polyphenols, and anthocyanins, on diseases such as anxiety, depression, and Alzheimer's and Parkinson's diseases. In conclusion, for human nutrition berry fruit supplementation might be an excellent source of antioxidant and alternative for prevention and reduction of symptoms in diseases such as anxiety, depression, Alzheimer's, and Parkinson's.