Pharmacology and toxicology of Peumus boldus and Baccharis genistelloides

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Abstract

There are a great number of medicinal plants without any scientific confirmation about their efficacy and safety. This paper is a short review about two medicinal plants, "boldo do chile" (Peumus boldus) and "carqueja" (Baccharis genistelloides). Pharmacological studies have confirmed several popular indications for P. boldus and B. genistelloides, besides have established a relationship between isolated compounds from these extracts and the pharmacological effects observed. On the other hand, toxicological researches have pointed out that P. boldus tea should not be consumed during a long period (potential hepatotoxicity) and by pregnant, especially during the first three months. Moreover, B. genistelloides tea must be prohibited for pregnant because of confirmed abortive action, and for patients using medicines for blood pressure disorders. These studies point out the continuous necessity of more studies about medicinal plants; only with this knowledge it will be possible a safe and efficient use.

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Ruiz, A. L. T. G., Taffarello, D., Souza, V. H. S., & Carvalho, J. E. (2008). Pharmacology and toxicology of Peumus boldus and Baccharis genistelloides. Revista Brasileira de Farmacognosia. Sociedade Brasileira de Farmacognosia. https://doi.org/10.1590/S0102-695X2008000200025

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