Human Papillomavirus (HPV)-Related Multiphenotypic Sinonasal Carcinoma With Intracranial Extension and Rapid Recurrence: A Case Report

Abstract

HPV-related multiphenotypic sinonasal carcinoma (HMSC) is a rare malignancy of the nasal cavity or paranasal sinuses that often presents with indolent behavior despite aggressive histologic appearance. Herein, we present an unusual case of a patient with HMSC presenting with rapid local recurrence, highlighting the histopathology and diagnostic and therapeutic strategies surrounding HMSC.