Hypo, hype and ’hyp’ human proteins

Abstract

Genes with unknown function are called orphan genes while their transcripts and peptides are called ypothetical proteins. There are many genes and their associated proteins that remain uncharacterized in the human genome. A database of human hypothetical prtoeins with ascribed functions could be helpful for biologists to search for potential proteins of interest. In recent years, the rapid completion of genome sequences has created essential information to link genes to gene products. In order to better explain functions fo un-annotated proteins we designed BioinformaTRICKS (an open source project) and used it to develop a database called HYPO