Pathophysiology of Subarachnoid Hemorrhage, Early Brain Injury, and Delayed Cerebral Ischemia

Abstract

Subarachnoid hemorrhage (SAH) has high morbidity and mortality rates because there is no sufficient treatment so far. The major topics in SAH research focus on early brain injury and delayed cerebral ischemia causing neurological deficits and bad outcome. Therefore understanding of the underlying mechanisms of SAH is mandatory for the development of successful SAH treatment strategies. In this chapter, we summarize the pathophysiology of subarachnoid hemorrhage, including early brain injury and delayed cerebral ischemia.