Off-the-shelf TCR for graft-versus-leukemia without GVHD

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Abstract

In this issue of Blood, Dossa et al report the engineering of T-cell receptor (TCR) transgenic T cells against the human minor histocompatibility antigen HA-1 for the prevention or treatment of leukemia relapse after allogeneic stem cell transplantation.

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Locke, F. L., & Anasetti, C. (2018). Off-the-shelf TCR for graft-versus-leukemia without GVHD. Blood, 131(1), 5–7. https://doi.org/10.1182/blood-2017-11-812990

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