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Enhanced oxidative killing of azole-resistant Candida glabrata strains with ERG11 deletion

Antimicrobial Agents and Chemotherapy (1996) 40(7) 1717-1719
DOI: 10.1128/aac.40.7.1717
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Abstract

The susceptibility of genetically defined Candida glabrata strains to killing by H2O2 and neutrophils was assessed. Fluconazole-susceptible L5L and L5D strains demonstrated survival rates higher than those of two fluconazole-resistant strains lacking the ERG11 gene coding for 14α- demethylase. Fluconazole resistance can occur by mechanisms which increase fungal susceptibility to oxidative killing by H2O2 and neutrophils.

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APA

Kan, V. L., Geber, A., & Bennett, J. E. (1996). Enhanced oxidative killing of azole-resistant Candida glabrata strains with ERG11 deletion. Antimicrobial Agents and Chemotherapy, 40(7), 1717–1719. https://doi.org/10.1128/aac.40.7.1717

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