Evaluation of antibiotic-impregnated mesh in preventing the recurrence of capsular contracture

Abstract

Background: Capsular contracture (CC) is the most frequently reported complication following breast augmentation. A growing body of evidence implicates subclinical (biofilm) infection around breast implants as an important cause of CC; however, effective prophylactic and treatment modalities remain controversial. Objectives: This article aims to review a single surgeon's experience using an antibiotic-impregnated mesh as a prophylactic measure against biofilm formation and recurrent CC. Methods: This study retrospectively reviewed 5 consecutive patients presenting with CC (Baker grades III and IV) who were managed by capsulectomy with implant replacement and simultaneous insertion of an antibiotic-impregnated mesh. Patient demographics and major complications were recorded, including CC recurrence, reoperation, and infection. Results: Complete correction of the contracture with no recurrence was achieved in all patients at a median followup of 25 months. Conclusions: This study demonstrates a novel technique using an antibiotic mesh to reduce bacterial access to breast implants at the time of insertion. Further investigation is warranted with more clinical cases in order to recommend this technique for the management of subclinical infection and CC. Level of Evidence: 4: