An autophagy-independent function of Beclin 1 in cancer

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Abstract

The involvement of Beclin 1 in cancer has been attributed primarily to its role in autophagy initiation. Our recent findings identify a novel alternative mechanism by which Beclin 1 can affect tumor progression through the regulation of growth factor receptor signaling.

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Rohatgi, R. A., & Shaw, L. M. (2016). An autophagy-independent function of Beclin 1 in cancer. Molecular and Cellular Oncology, 3(1). https://doi.org/10.1080/23723556.2015.1030539

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