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Viral therapies for glioblastoma and high-grade gliomas in adults: a systematic review

Neurosurgical Focus (2021) 50(2) 1-14
DOI: 10.3171/2020.11.FOCUS20854
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Abstract

OBJECTIVE High-grade gliomas (HGGs) inevitably recur and progress despite resection and standard chemotherapies and radiation. Viral therapies have emerged as a theoretically favorable adjuvant modality that might overcome intrinsic factors of HGGs that confer treatment resistance.

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Wang, J. L., Scheitler, K. M., Wenger, N. M., & Elder, J. B. (2021). Viral therapies for glioblastoma and high-grade gliomas in adults: a systematic review. Neurosurgical Focus, 50(2), 1–14. https://doi.org/10.3171/2020.11.FOCUS20854

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