Eukaryotic initiation factor 5

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Abstract

Eukaryotic initiation factor 5 (eIF-5) is an important factor in translation initiation. It acts as a GTPase activating factor to mediate the hydrolysis of GTP binding to eIF-2 which is essential for the composition of functional 80S complex. Besides, eIF-5 binds eIF-2 and eIF-3 at the same time, so induces the construction of translation initiation factors complex.

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Wan, Y. Q., Zhu, K. Y., Wang, S. Z., & Xie, W. (2002, February). Eukaryotic initiation factor 5. Progress in Biochemistry and Biophysics. https://doi.org/10.1007/978-3-642-16483-5_2037

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