Effect of chromium supplementation on chromium status, insulin and glucose level in Non-insulin Dependent Diabetes Mellitus (NIDDM) subjects

Abstract

The effects of supplemental Cr picolinate on body Cr state, serum insulin and blood sugar in 20 NIDDM subjects was studied. Subjects were divided into a treatment and control group, 10 subjects for each group. Three subjects dropped out of the study. Median value of Cr serum was 0, 09 μg/L with a range of 0, 01-0, 48 μg/L. There was no significant difference for the body Cr state expressed as relative chromium response, serum insulin as well as blood sugar between the two groups after supplementation of 500 μg/daily of Cr picolinate for 4 weeks. These datas showed that the effect of Cr supplementation on body Cr state, serum insulin and blood sugar in NIDDM subjects was not statistically significant.