Synthesis and biocidal activity of novel N-halamine hydantoin-containing polystyrenes

Abstract

Three homopolymers containing hydantoin substituents were obtained by chemical modification of reactive p-chloromethylated polystyrene. The prepared polymers were chlorinated to yield N-halamine materials with biocidal properties. The chemical structure of polymers was characterized by Fourier transform infrared spectroscopy and nuclear magnetic resonance spectroscopy. All of the hydantoin polymers are insoluble in water and common organic solvents. Microbiological investigations prove the high biocidal activity of the obtained chlorinated polystyrene derivatives containing spirohydantoin moieties. The obtained polymers will be useful in designing and constructing medical and pharmaceutical equipment. The ability to crosslink allows to expect easy grafting of these biocidal macrochains, for example, on textiles.