The high prevalence of inability and functional dependence is an important problem in elderly people. It is closely related with aging decrease of lean muscle mass that occurs even in healthy subjects. Skeletal muscle mass deficiency, or sarcopenia, results from complex interactions between innervations disturbances, hormones deficiency, inflammatory cytokines and restriction in caloric-proteic ingestion. Loss of skeletal muscle mass and strength results in disability and functional dependency that are associated to frailty in many elderly people. These conditions represent enormous economic and social budget. In this article, we evaluate pathogenesis of sarcopenia and discuss potential therapies.
CITATION STYLE
de Araujo Silva, T. A., Frisoli Junior, A., Medeiros Pinheiro, M., & Szejnfeld, V. L. (2006). Sarcopenia Associada ao envelhecimento: Aspectos etiológicos e opções terapêuticas. Revista Brasileira de Reumatologia, 46(6), 391–397. https://doi.org/10.1590/s0482-50042006000600006
Mendeley helps you to discover research relevant for your work.