Low-temperature study of a new nevirapine pseudopolymorph

Abstract

The title compound (systematic name: 11-cyclo-propyl-4-methyl-5,11-dihydro- 6H-dipyrido[3,2-b:2′,3′-e][1,4]diazepin-6-one butanol 0.3-solvate), C15H14N4O·0.3C4H9OH, was crystallized in a new triclinic pseudopolymorphic form, a butanol solvate, and the crystal structure determined at 150 K. The mol-ecular conformation of this new form differs from that reported previously, although the main inter-molecular hydrogen-bond pattern remains the same. N - H⋯O hydrogen bonds [N⋯O = 2.957 (3) Å] form centrosymmetric dimers and the crystal packing of this new pseudopolymorph generates infinite channels along the b axis. © International Union of Crystallography 2008.