Vicarious nucleophilic substitution of (chloroalkyl)heterocycles with nitroarenes

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Abstract

The vicarious nucleophilic substitution of potassium carbanions of the (chloromethyl)pyridines 1a and 1b, (chloromethyl)benzothiazole 1c, (chloromethyl)thiazole 1d, (chloroethyl)thiazole 1e and (chloroethyl) benzothiazole 1f wit nitroarenes, leading to nitrobenzyl heterocycles 2 and 4-14 has been studied. © Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.

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Florio, S., Lorusso, P., Luisi, R., Granito, C., Ronzini, L., & Troisi, L. (2004). Vicarious nucleophilic substitution of (chloroalkyl)heterocycles with nitroarenes. European Journal of Organic Chemistry, (10), 2118–2124. https://doi.org/10.1002/ejoc.200300806

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