Journal Article

Benzotriazol-1-ylmethyl isocyanide, a new synthon for CHNC transfer. Syntheses of α-hydroxyaldehydes, 4-ethoxy-2-oxazolines and oxazoles

Tetrahedron Letters (1989) 30(48) 6657-6660
DOI: 10.1016/S0040-4039(00)70643-5
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Abstract

Readily prepared benzotriazol-1-ylmethyl isocyanide (BetMIC) reacts under mild conditions with ketones and aldehydes, to afford oxazolines (convertible into α-hydroxyaldehydes) and oxazoles, respectively. © 1989.

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Katritzky, A. R., Chen, Y. X., Yannakopoulou, K., & Lue, P. (1989). Benzotriazol-1-ylmethyl isocyanide, a new synthon for CHNC transfer. Syntheses of α-hydroxyaldehydes, 4-ethoxy-2-oxazolines and oxazoles. Tetrahedron Letters, 30(48), 6657–6660. https://doi.org/10.1016/S0040-4039(00)70643-5

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