Synthesis and cytotoxic evaluation of novel thiazolocarbazoles

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Abstract

Novel thiazolocarbazole derivatives 4 and 5 have been synthesized via the corresponding imino-1,2,3-dithiazoles 3. In vitro antitumor activity of these polyheterocyclic compounds was studied and the results show that 2-cyano derivatives exhibit a medium in vitro antiproliferative effect.

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Lamazzi, C., Chabane, H., Thiery, V., Pierre, A., Leonce, S., Pfeiffer, B., … Besson, T. (2002). Synthesis and cytotoxic evaluation of novel thiazolocarbazoles. Journal of Enzyme Inhibition and Medicinal Chemistry, 17(6), 397–401. https://doi.org/10.1080/1475636021000005703

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