New ursane triterpene from the fruits of Terminalia arjuna

Abstract

A new ursane triterpene, torment (2α,3β,19α-trihydroxyurs- 12-en) (1), was isolated from the fruits of Terminalia arjuna along with four known ursane and oleane triterpenes. The structures were established on the basis of extensive NMR (1D & 2D) and MS (EI & ESI) studies. Tormentic acid (2), 19α-hydroxy asiatic acid (3) and olean-12-en-2α,3β- diol (4) were isolated for the first time from this species. Compounds 1 and 2 lacked significant enzyme inhibition, cytotoxicity, immunomodulatory and antiglycation activities.