Sarcomas of the sinonasal tract

Abstract

Background: Sinonasal sarcomas are rare and heterogeneous in nature. Continuously collecting data influencing the prognosis is fundamental for optimizing therapeutic assessment of this highly destructive neoplasm. Methods: We conducted a single-institution retrospective cohort study considering 27 patients with sinonasal sarcoma. Results: The overall survival (OS) rates for 1 year and 5 years were calculated as 74% and 36%, respectively. Extent of the primary tumor (P =.010), nodal spread (P =.009), and age (P =.004) significantly reduced the OS. Disease-free survival (DFS) was significantly reduced by age (P =.003), extent of the primary (P =.006), nodal (P =.004), and hematogenous (P =.048) spread. Multimodal therapy including surgery improved the OS and DFS rates (P