Two-photon-triggered drug delivery in cancer cells using nanoimpellers

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Abstract

A therapy of cancer cells: Two-photon-triggered camptothecin delivery (see picture) with nanoimpellers was studied in MCF-7 breast cancer cells. A fluorophore with a high two-photon absorption cross-section was first incorporated in the nanoimpellers. Fluorescence resonance energy transfer (FRET) from the fluorophore to the azobenzene moiety was demonstrated. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Croissant, J., Maynadier, M., Gallud, A., Peindy N’Dongo, H., Nyalosaso, J. L., Derrien, G., … Zink, J. I. (2013). Two-photon-triggered drug delivery in cancer cells using nanoimpellers. Angewandte Chemie - International Edition, 52(51), 13813–13817. https://doi.org/10.1002/anie.201308647

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