Tetrodotoxin. Vll. On the Structures of Tetrodotoxin and its Derivatives

Abstract

The structures of both tetrodonic acid hydrobromide and 6,11-diacetylanhydrotetrodotoxin hydroiodide were established by chemical and X-ray crystallographical research. Based upon structures of both these salts and upon other chemical information, we determined that tetrodotoxin and anhydrotetrodotoxin have zwitterionic hemilactal structures. © 1964, The Pharmaceutical Society of Japan. All rights reserved.