Antibacterial, allelopathic and antioxidant activity of extracts and compounds from rourea induta planch. (Connaraceae)

Abstract

This study evaluated some biological activities of the leaves from Rourea induta Planch., Connaraceae. Fractions of the ethanolic extract from leaves of this species were obtained by liquid/liquid partition and their antibacterial, allelophatic and antioxidant activitieswere analyzed. By the agar diffusion method the ethyl acetate, chloroform fractions and hyperin showed antimicrobial activity against Staphylococcus epidermidis with an inhibition halo of 15.0, 12.3 and 9.3 mm respectively, and Staphylococcus aureus with 7.6 mm for the fractions. For antioxidant activity all samples have demonstrated a significant potential, especially the chloroform, ethyl acetate fractions and the hyperin which IC50 were, 5.33 ±0.19; 3.21 ± 0.00 and 3.89 ± 0,02 respectively. This result is close to the standards vitamin C and rutin. In the allelopathic activity the hexane fraction at 0.8 mg and 0.4 mg, inhibited 33.24% and 20.54% the hipocotyl's growth of Lactucasativa seeds, and the compound tetracosane inhibited 18.05% the hipocotyl's growth at 0.4 mg. The obtained results stimulate the continuity of this study.