CYR61/CCN1: A Novel Mediator of Epidermal Hyperplasia and Inflammation in Psoriasis¿

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Abstract

The complex pathogenesis of psoriasis is still not fully understood. The study by Sun et al. (2015) suggests that CYR61 (now named CCN1), a secreted matricellular protein, has a role in the pathogenesis of psoriasis, and thus targeting CCN1 represents a potential therapeutic strategy in its treatment.

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Quan, T., Johnston, A., Gudjonsson, J. E., & Fisher, G. J. (2015, November 1). CYR61/CCN1: A Novel Mediator of Epidermal Hyperplasia and Inflammation in Psoriasis¿. Journal of Investigative Dermatology. Nature Publishing Group. https://doi.org/10.1038/jid.2015.300

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