Regulation of adrenal ornithine decarboxylase by adrenocorticotropic hormone and cyclic AMP

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Abstract

ACTH stimulates rat adrenal ornithine decarboxylase activity. This effect may be mediated by cyclic AMP. However, cyclic AMP does not appear to be a determinant of the high level of enzyme activity found in adrenocortical cancer.

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Richman, R., Dobbins, C., Voina, S., Underwood, L., Mahaffee, D., Gitelman, … Ney, R. L. (1973). Regulation of adrenal ornithine decarboxylase by adrenocorticotropic hormone and cyclic AMP. Journal of Clinical Investigation, 52(8), 2007–2015. https://doi.org/10.1172/JCI107385

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