Activation of electrophile/nucleophile pair by a nucleophilic and electrophilic solvation in a SNAr reaction

9Citations
Citations of this article
24Readers
Mendeley users who have this article in their library.

Abstract

Nucleophilic aromatic substitution reactions of 4-chloroquinazoline toward aniline and hydrazine were used as a model system to experimentally show that a substrate bearing heteroatoms on the aromatic ring as substituent is able to establish intramolecular hydrogen bond which may be activated by the reaction media and/or the nature of the nucleophile.

Cite

CITATION STYLE

APA

Sánchez, B., Calderón, C., Tapia, R. A., Contreras, R., & Campodónico, P. R. (2018). Activation of electrophile/nucleophile pair by a nucleophilic and electrophilic solvation in a SNAr reaction. Frontiers in Chemistry, 6(OCT). https://doi.org/10.3389/fchem.2018.00509

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free