GC-MS Analysis, Heavy Metals, Biological, and Toxicological Evaluation of Reseda muricata and Marrubium vulgare Methanol Extracts

Abstract

The usage of herbal remedy is growing vividly all around the world. Though, ecological contamination particularly with heavy metals carriages thoughtful problem on quality of medicinal plants and their foodstuffs. In the world, 80% of the population depend on traditional medicine, while information on the levels of heavy metal such as Zn, Mn, Cu, Cr, Pb, As, Cd, and Cr in plants utilized for making of herbal remedies is unavailable. Therefore, the purpose of this study was to assess phytochemicals, biological activities, and heavy metal analysis of Reseda muricata and Marrubium vulgare grown in different parts of Saudi Arabia. Qualitative phytochemical analysis of R. muricata and M. vulgare confirmed the presence of alkaloids, flavonoids, tannins, phenol, and saponins. Methanol extracts of both Reseda muricata and Marrubium vulgare were characterized with the help of GC-MS. Antioxidants, antimicrobial, and brine sharp lethal toxicity of the both species were also evaluated.