Immunohistochemistry (IHC) plays an important role in the diagnosis of some bone tumors, especially in the differential diagnosis of primary from metastatic non-osseous tumors and in the categorization of small-round-blue-cell tumors. Use of two positive and two negative markers is ideal to improve the specificity. Choice of markers depends upon what tumors are logically within differential diagnosis after seeing the morphology, in correlation with clinical and radiological details provided to the pathologist. Our present article reviews immunomarkers used in bone tumors and their diagnostic significance.
CITATION STYLE
M, S., & I, S. R. (2014). Utility of immunohistochemistry in the diagnosis of bone tumors. Journal of Medical and Scientific Research, 2(2), 84–90. https://doi.org/10.17727/jmsr.2014/2-016
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