Surface-engineered quantum dot nanocomposites for neurodegenerative disorder remediation and avenue for neuroimaging

Abstract

This review investigates the potential of surface-engineered quantum dot (QD) nanocomposites in the treatment of neurodegenerative disorders and their use in neuroimaging. QDs possess distinctive properties such as adjustable fluorescence and adaptable surface modification, making them useful for both targeted drug administration and precise imaging in the complex nervous system. The report provides a concise overview of progress and obstacles, with a particular focus on concerns regarding biocompatibility, potential toxicity, and the ability to cross the blood-brain barrier. The importance of continuous research in surface engineering, biocompatibility investigations, and standardization of synthesis procedures is emphasized as essential measures to overcome these obstacles. Although there are challenges, the review highlights the significant potential of surface-engineered QD nanocomposites to transform our understanding of neurodegenerative disorders and improve neuroimaging techniques. This could lead to better diagnostic and therapeutic approaches for neurological health in the future.