Animal studies

Abstract

Endometriosis can be defined as the presence of endometrial glandular and stromal cells outside the uterine cavity. The prevalence of the disease in the general population is unknown, but among women with infertility the prevalence has been shown to range from 13-33%.1 Endometriosis is a progressive disease in 40-50% of women of reproductive age.2 The most frequent sites of implantation are the pelvic area and the peritoneum. The disease varies in appearance from a few minimal lesions on pelvic linings to massive ovarian endometriotic cysts that distort tubo-ovarian architecture and characteristic extensive adhesions often involving bowel, bladder, and ureter.3.