Tumour-like lesions of the spleen

Abstract

Tumour-like lesions of the spleen are very rare lesions but can cause diagnostic confusion due to their varying morphologic patterns. These lesions behave in a benign fashion. Included in this group are hamartomas, sclerosing angiomatoid nodular transformation (SANT), inflammatory pseudotumors, and possibly IgG4-related disease. Clinically, these lesions are often discovered incidentally on imaging or at autopsy. However radiological and morphological findings can be misleadingly worrisome. It is therefore important to be familiar with these lesions to distinguish them from malignant lesions.