Inhibitors of melanogenesis, oh-3984 kl and k2 II. Physico-chemical properties and structural elucidation

Abstract

Newmelanin synthesis inhibitors, OH-3984Kl and K2, were isolated from the fermentation broth of Streptomyces sp. OH-3984,and their structures were elucidated by spectroscopic methods and by chemical transformations. OH-3984 Kl (M.W.: 306; C18H26O4) and K2 (M.W.: 308; Ci8H28O4) have unique y-lactone rings, both of which corresp. © 1993, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.