Cardiac resynchronization therapy following carillonVR annuloplasty device for symptomatic heart failure and functional mitral regurgitation: A case report

Abstract

Background Symptomatic patients with significant left ventricular systolic dysfunction (LVSD) require a tailored treatment approach. Both functional mitral regurgitation (FMR) and left bundle branch block (LBBB) can develop, contributing to clinical deterioration, and worse prognosis despite optimal medical therapy (OMT). Case summary We report the case of a symptomatic 60-year-old man on OMT with LVSD and significant FMR. His symptoms and FMR initially improved following transvenous mitral annuloplasty using the CarillonVR Mitral Contour SystemVR annuloplasty device. However, he subsequently developed LBBB with associated reduction in exercise capacity, for which he underwent cardiac resynchronization therapy, and ensuing symptom improvement and stabilization. Discussion Our case describes how targeted device interventions can be combined synergistically to optimize patient symptoms.