2-Hydroxy-4,6-dimethoxyacetophenone from leaves of Peperomia glabella

Abstract

The 2-hydroxy-4,6-dimethoxyacetophenone was isolated from the leaves of the Peperomia glabella (Piperaceae family). The molecule crystallizes in the space group P1̄ with two independent molecules in the asymmetric unit. The structural analysis reveals an infinite two-dimensional network in the (011) plane, stabilized by intermolecular hydrogen bonds along [100] and van der Waals interactions along [011], The molecules present strong intra-molecular hydrogen bonds [O1-HO1...O4 = 1.53(2) Å and O5-HO5...O8 = 1.38(2) Å], The molecular conformation was analyzed using the MOGUL, a knowledge base of molecular geometry derived from the CSD (Cambridge Structural Database). © 2006 Sociedade Brasileira de Química.