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Molecular and Functional Characteristics of APJ

  • Hosoya M
  • Kawamata Y
  • Fukusumi S
  • et al.
Journal of Biological Chemistry (2000) 275(28) 21061-21067
DOI: 10.1074/jbc.m908417199
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Abstract

We have recently identified apelin as the endogenous ligand for human APJ. In rats, the highest expression of APJ mRNA was detected in the lung, suggesting that APJ and its ligand play an important role in the pulmonary system. When apelin-36 and its pyroglutamylated C-terminal peptide, [

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Hosoya, M., Kawamata, Y., Fukusumi, S., Fujii, R., Habata, Y., Hinuma, S., … Fujino, M. (2000). Molecular and Functional Characteristics of APJ. Journal of Biological Chemistry, 275(28), 21061–21067. https://doi.org/10.1074/jbc.m908417199

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