Antimicrobial peptides from the hemolymph of the prawn Macrobrachium rosenbergii

Abstract

The study was carried out to find the antimicrobial activity of hemolymph of Macrobrachium rosenbergii and to evaluate the antimicrobial compounds. The highest inhibition was observed against Staphylococcus aureus, Lactobacillus vulgaris and Klebsiella pneumoniae (12 mm). Antifungal activity was observed only against Fusarium moniliforme (11 mm). Antimicrobial peptide was characterized in molecular size ranging from 22 to 91 KDa with antimicrobial activity against various infectious pathogens. Hemolymph plays a vital role in the disease prevention in crustaceans and there is no report on antimicrobial activities of the prawn M. rosenbergii.