Gastric inflammatory fibroid polyp treated with Helicobacter pylori eradication therapy

Abstract

Gastric inflammatory Fibroid polyps (IFPs) are rare benign lesions that occur in the distal stomach. We describe a 56-year-old woman with Helicobacter pyloti (H. pylori)-positive gastric IFP treated with eradication. Endoscopic examination revealed a submucosal tumor, 35 mm in diameter, with an ulcerated apex at the antrum. H. pylori were positive by both histology and tissue culture, and eradication (a proton pump inhibitor, amoxicillin, and clarithromycin) was performed. After 6 months, the tumor morphologically changed and decreased in size. This case suggests that H. pylori may play a role in the pathogenesis of gastric IFPs. © 2007 The Japanese Society of Internal Medicine.