A convenient one-pot procedure for the selective reduction of ketones in the presence of aldehydes

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Abstract

The title process has been accomplished by a three-step sequence involving protection of aldehyde as the imine, in situ reduction of ketone with lithium tri-tert-butoxyaluminohydride, and regeneration of aldehyde on hydrolytic work-up. © 1980.

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Paradisi, M. P., Zecchini, G. P., & Ortar, G. (1980). A convenient one-pot procedure for the selective reduction of ketones in the presence of aldehydes. Tetrahedron Letters, 21(52), 5085–5088. https://doi.org/10.1016/S0040-4039(00)71141-5

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