Plasmodium falciparum multiplicity correlates with anaemia in symptomatic malaria

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Abstract

In 366 Ghanaian children with symptomatic Plasmodium falciparum malaria, low haemoglobin levels and severe anaemia were associated with a high multiplicity of infection (MOI) and with distinct merozoite surface protein alleles. High MOI not only reflects premunition but may also contribute to anaemia in symptomatic malaria.

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Mockenhaupt, F. P., Ehrhardt, S., Eggelte, T. A., Markert, M., Anemana, S., Otchwemah, R., & Bienzle, U. (2003). Plasmodium falciparum multiplicity correlates with anaemia in symptomatic malaria. Tropical Medicine and International Health, 8(10), 857–859. https://doi.org/10.1046/j.1365-3156.2003.01117.x

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