DNA: Beyond the Double Helix

Abstract

Reciprocal exchange can be used to produce DNA motifs based on branching at the level of secondary structure. These motifs can be combined by sticky-ended cohesion to produce a variety of structures. Stick polyhedra and nanomechanical devices have been produced by self-assembly from motifs based on branched DNA. Periodic arrays with tunable surface features has also been produced; aperiodic arrangements have been used for DNA-based computation.