Basic protein structure prediction for the biologist: A review

Abstract

As the field of protein structure prediction continues to expand at an exponential rate, the bench-biologist might feel overwhelmed by the sheer range of available applications. This review presents the three main approaches in computational structure prediction from a non-bioinformatician?s point of view and makes a selection of tools and servers freely available. These tools are evaluated from several aspects, such as number of citations, ease of usage and quality of the results. Finally, the applications of models generated by computational structure prediction are discussed.nema