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The telomeric PARP, tankyrases, as targets for cancer therapy

British Journal of Cancer
DOI: 10.1038/sj.bjc.6602951
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Abstract

The requirement for the maintenance of telomeres by telomerase by most cancer cells for continued proliferation is a target in anticancer strategies. Tankyrases are poly(ADP-ribose) polymerases that enhance telomerase access to telomeres. Tankyrase 1 modulates telomerase inhibition in human cancer cells and is reviewed in this report as a potential telomere-directed anticancer target. © 2006 Cancer Research UK.

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Seimiya, H. (2006, February 13). The telomeric PARP, tankyrases, as targets for cancer therapy. British Journal of Cancer. https://doi.org/10.1038/sj.bjc.6602951

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