Ileus after administration of cold remedy in an elderly: Diabetic patient treated with acarbose

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Abstract

A 69-year-old type 2 diabetic man was admitted due to diabetic gangrane, He had a history of subtotal gastrectomy. During hospitalization, he was treated with regular insulin and 300 mg/ day of acarbose, He developed a low grade fever, cough and nasal discharge, and was given a compound "cold" remedy with anticholenergic properties. The next day, he suffered from a paralytic ileus. Oral intake and acarbose were withheld and the ileus spontaneously resolved after 2 days. These finding indicate the possibility that the ileus was triggered by drugs with anticholinergic properties in this elderly diabetic patient treated with α-glucosidase inhibitors.

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Oba, K., Kudo, R., Yano, M., Watanabe, K., Ajiro, Y., Okazaki, K., … Metori, S. (2001). Ileus after administration of cold remedy in an elderly: Diabetic patient treated with acarbose. Journal of Nippon Medical School, 68(1), 61–64. https://doi.org/10.1272/jnms.68.61

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