Comparative study to evaluate lipid profile in smoking and non-smoking individual at tertiary care centre

Abstract

Background:  Cigarette smoking, which is considered a major risk factor for atherosclerosis and coronary heart disease, may lead to changes in normal plasma lipid profile. The aim of the study was to evaluate the effect of cigarette smoking on lipid parameters in smokers and non-smokers. Material and Methods: A cross sectional comparative study was carried out in 200 subjects. The subjects were divided into two groups. Group A consisted of 100 smokers and Group B consisted of 100 Non-smokers. After overnight fasting following laboratory investigations were done in all subjects, Serum total cholesterol, Serum high density lipoprotein (HDL), Serum low density lipoprotein (LDL), Serum very low-density lipoprotein (VLDL), Serum triglyceride (TGL), Fasting blood sugar (FBS), Serum Creatinine, Urine for albumin, sugar and microscopic examination and the results of these tests were compared between the two groups.Results: All the values of lipid profile, TC, HDL, LDL, VLDL, TGL, were found to be significantly higher among the smokers compared to the non-smokers. The mean value of HDL was higher in non-smokers when compared to that of smokers and were statistically significant.