Abstract
Methods: A search was performed of the PubMed, EMBASE, and Wanfang databases. Data were extracted and pooled ORs with 95% CIs were calculated. Background: Several studies have examined associations between TNF-α polymorphisms and asthma risk, but the results have been conflicting. Results: Fifty-four studies were included. A significant association between the TNFA -308A/G polymorphism and asthma susceptibility was observed for AA+AG vs GG (OR, 1.39; 95% CI, 1.23-1.58; P
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Huang, H., Nie, W., Qian, J., Zang, Y., Chen, J., Lai, G., … Xiu, Q. (2014). Effects of TNF-α polymorphisms on asthma risk: A systematic review and meta-analysis. Journal of Investigational Allergology and Clinical Immunology, 24(6), 406–417.
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