Recent Advances in Niosomal Drug Delivery: A Review

Abstract

The production of niosomes, which are non-ionic surfactant vessels, involves hydrating synthetic non-ionic surfactants, either with or without the addition of cholesterol or another lipid. Due to their distinctive qualities, including biodegradability, biocompatibility, chemical stability, low production cost, ease of storage and handling, and low toxicity, non-ionic surfactant vesicles also known as niosomes have received a lot of attention in the field of modern drug delivery system. Niosomes are hydrated vesicular systems with a lamellar bilayer structure made of non-ionic surfactants with or without cholesterol, and they have a wide spectrum of solubilities that allow them to encapsulate a variety of bioactive chemicals. Niosomes have been tested as a delivery system for a variety of anti-cancer medications, genes, antigens, and other bioactive substances. This article focuses on recent developments in niosomal drug delivery, possible benefits over alternative delivery mechanisms, formulation techniques, characterisation techniques, and ongoing niosome research.