Retracted : Comparison of vildagliptin and glimepiride: effects on glycaemic control, fat tolerance and inflammatory markers in people with Type 2 diabetes

Abstract

Vildagliptin was found to cause greater reductions in fasting plasma insulin levels and post‐oral fat load insulin peak compared with glimepiride. The homeostatic model assessment of insulin resistance index was shown to increase with glimepiride and decrease with vildagliptin. Vildagliptin increased the insulin sensitivity index compared with glimepiride. Vildagliptin reduced total cholesterol and LDL cholesterol levels, both during fasting and after an oral fat load test. Vildagliptin increased adiponectin and reduced high‐sensitivity C‐reactive protein levels, both during fasting and after an oral fat load test.