Isolation and Identification of Nicotiflorin and Narcissin from the Aerial Parts of Peucedanum aucheri Boiss.

Abstract

Peucedanum aucheri Boiss. (Apiaceae) is a herbaceous wild plant native to Iran and is used in Iranian folk medicine as a diuretic and for the treatment of kidney disorders. Phytochemical investigation of different extracts prepared from the aerial part of P. aucheri Boiss. resulted to the isolation of two main flavonol glycosides from methanolic extract. Using comprehensive spectroscopic methods, including 1D and 2D nuclear magnetic resonance (NMR) spectroscopy and mass spectroscopy, chemical structure of isolated compounds were determined as kaempfrol-3-o-rutinoside (nicotiflorin) and isorhamnetin-3-o-rutinoside (narcissin). Although narcissin has previously been isolated from P. ruthenicum, to the best of our knowledge, isolation of nicotiflorin from Peucedanum genus is reported for the first time.